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Science
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Departments | DOCTORS

Dots

Our dedicated doctors lead groundbreaking research in HIV prevention, vaccine development, and infectious diseases. With extensive experience in clinical trials, they ensure the highest standards of safety and scientific integrity. Committed to both medical innovation and community well-being, our team is shaping the future of healthcare.

Dr PL Kotzé

Qualifications
Qualifications Field of Study University Year Completed
MBChB Medicine UOFS 1980
Master in Internal Medicine Medicine UOFS 1988
Work Experience
Period Position Employer
1988 – Current Private Practice Private Practice
2007 – Current Principal Investigator / Sub-Investigator Qhakaza Mbokodo Research Clinic
Studies
Year Protocol Number Designation
2006 – 2007 TMC 114 –C211 Sub-Investigator
2006 – 2007 A4001026 Sub-Investigator
2007 – 2009 IPM 100 Principal Investigator
2009 – 2010 IPM 014A Co-Investigator
2010 IPM 015 Principal Investigator
2012 – 2016 IPM 027 Principal Investigator
2012 - 2015 FACTS 001 Sub-Investigator
2016 - 2019 IPM 032 Principal Investigator
2012 – 2016 IPM 007 Principal Investigator
2016 – Current HVTN 108 Principal Investigator
2017 – Current HVTN 702 Principal Investigator
2018 - Current HVTN 705/ HPX 2008 Principal Investigator
2020 - Current HVTN 405/ HPTN 1901 Principal Investigator
2020 – Current VAC31518COV3001 Principal Investigator
2021 - Current CoVPN 5001 Principal Investigator
2021 - Current VAC31518COV3012 Principal Investigator
2021 - Current CoVPN 3008 Principal Investigator
2021 - Current MK8591-022 Principal Investigator
2021 – Current VAC31518COV30XX Principal Investigator
2022 – Current Sisonke 4 (SHERPA) / mRNA-1273-P508 Principal Investigator
2022 – Current INSIGHT Cohort Principal Investigator
2022 – Current GS-US-412-5624 Sub-Investigator
2023 – Current MK8591A-053 Sub-Investigator
2024 - Current HVTN 605/A5421 Sub-Investigator
2024 - Current MK8527-007 Principal Investigator
2024 - Current Gates MRI-TBV02-301 Sub-Investigator
2024 - Current Pfizer C3671032 Sub-Investigator
Peer-reviewed publications
  1. Diaphragm pacing in the treatment of ventilator failure – SAMJ; 17 August 1985.
  2. The role of the Physician in Hypertension – Specialist Medicine; February 1993.
  3. Treating the early elderly with Hypertension and Diabetes – General Practitioners Journal by fax (02 July 2000 and 9 July 2000).
  4. Hypertension in the elderly patient with diabetes: Treatment and cost of treatment - CME; June 2000.
  5. HIV Incidence Remains High in KwaZulu-Natal, South Africa: Evidence from Three Districts; PLoS ONE; April 2012.
  6. Adherence Improvement Innovations to Enhance Protocol Compliance and Vaginal Ring Adherence in a Phase III HIV Prevention Study in Kwa-Zulu Natal; AIDS Research & Human Retroviruses 30 Suppl 1 (S1); October 2014.
  7. Safety, Acceptability and Adherence of Dapivirine Vaginal Ring in a Microbicide Clinical Trial.
  8. Conducted in Multiple Countries in Sub-Saharan Africa; PLoS ONE; March 2016.
  9. Development and Validation of Measures to Screen for Potential Adherence and Support Adherence Prospectively, HIV Research for Prevention Conference; October 2016.
  10. Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women; New England Journal of Medicine; December 2016.
  11. Optimizing Adherence in HIV Prevention Product Trials: Development & Psychometric Evaluation of Simple Tools for Screening & Adherence Counselling; PLoS ONE; April 2018.
  12. Safety, Adherence and HIV-1 Seroconversion in Dream: An Open-label Dapivirine Vaginal Ring Trial - 9th SA AIDS Conference; June 2019.
  13. Long-term Follow-up of Seroconverters from Dapivirine Vaginal Ring Trials: The Ring Study and Dream - 9th SA AIDS Conference; June 2019.
  14. Age-Specific Risk Scores Do Not Improve HIV-1 Prediction Among Women in South Africa; JAIDS; July 2020.
  15. Vaccine Efficacy of ALVAC-HIV and Bivalent Subtype C gp120-MF59 in Adults; New England Journal of Medicine; March 2021.
  16. Quantifiable Plasma Tenofovir Among South African Women Using Daily Oral Pre-exposure Prophylaxis During The ECHO Trial; JAIDS; September 2022.
  17. Risk Factors Associated with HIV Acquisition in Males Participating in HIV Vaccine Efficacy Trials in South Africa; AIDS and Behavior; March 2023.
  18. Evaluation of Cross-Sectional HIV Incidence Recency Testing in Samples from the Evidence for Contraceptive Options and HIV Outcomes (ECHO) Trial; International AIDS Society; 23-26 July 2023.

Dr. NE Gracie

Qualifications
Qualifications Field of Study Institution Year Completed
Bachelor of Medicine & Bachelor of Surgery Medicine University of Pretoria 2011 - 2017
Intensive Medical Spanish & Introduction to Evidence Based Tropical Medicine Course Medicine IHCAI Foundation 2014
ECG Interpretation Course Level 1 Medicine Claassen & Claassen Training 2021
Basic Life Support for Health Care Providers Medicine Claassen & Claassen Training 2021
Advanced Cardiovascular Life Support Course Medicine Claassen & Claassen Training 2021
Paediatric Advanced Life Support Course Medicine Claassen & Claassen Training 2021
Post Graduate Diploma in Public Health Medicine University of Pretoria 2023-2024
Work Experience
Period Position Employer
May 2022 – Current Sub-Investigator/Principal Investigator Qhakaza Mbokodo Research Clinic
Jan 2021 – Dec 2021 Independent Practitioner South African National Defence Force – Area Military Health Unit (Gauteng)
Jan 2020 – Dec 2020 Community Service Practitioner South African National Defence Force – Area Military Health Unit (Gauteng)
Jan 2018 – Dec 2019 Medical Intern Groote Schuur Hospital
Studies
Year Protocol Number Designation
2022 – Current Sisonke 4 (SHERPA) / mRNA-1273-P508 Sub-Investigator
2022 – Current INSIGHT Cohort Sub-Investigator
2022 – Current GS-US-412-5624 Sub-Investigator
2022 – Current MK8591-022 Sub-Investigator
2022 – Current CoVPN 3008 Sub-Investigator
2023 – Current MK8591A-053 Principal Investigator
2024 – Current HVTN 605/A5421 Principal Investigator
2024 – Current MK8527-007 Sub-Investigator
2024 – Current Gates MRI-TBV02-301 Sub-Investigator
2024 – Current Pfizer C3671032 Sub-Investigator

Dr. J Kotze

Qualifications
Qualification Field of Study Institution Year Completed
FC Plast Surg (SA) Plastic Surgery College of Medicine of South Africa 2020
MMed Medicine University of Pretoria 2020
MBChB Medicine University of the Free State 2011
National Senior Certificate Matric Ladysmith High School 2006
Work Experience
Period Position Employer
Jun 2024 – Current Sub-Investigator Qhakaza Mbokodo Research Clinic
Oct 2022 – Current Senior Hand Surgery Fellow Guy’s and St Thomas’ NHS Foundation Trust – London
Jan 2022 – Jun 2022 Senior Hand Surgery Fellow University of Cape Town
Jan 2022 – Current PhD Candidate University of Pretoria
Jan 2021 – Dec 2021 Consultant Plastics Surgery Department of Health – Northern Cape
Jun 2017 – Jul 2022 Observership Breast Reconstruction KU Leuven University – Belgium
Oct 2015 – Oct 2020 Plastic Surgery Resident Department of Health – Pretoria
Jan 2014 – Sep 2015 Medical Officer Plastic Surgery Department of Health – Northern Cape
Jan 2012 – Dec 2013 Intern Doctor Department of Health – Port Shepstone
Peer-reviewed publications
  1. Percutaneous puncture of flexor sheath ganglions: an assessment of recurrence. Journal of Hand Surgery (European Volume). Sep 2022.
  2. The antimicrobial effect of Thromboseel against multidrug resistant and drug-sensitive organism: an in vitro study. South African Journal of Plastic & Reconstructive Aesthetic Surgery & Burns. Feb 2022.
  3. Management of acute complex traumatic wound with a dermal regeneration template: Case Report. South African Journal of Surgery. Feb 2017.
  4. Mobile phones for plastic surgery and burns: Current practice. Encyclopedia of Mobile Phone Behaviour. Mar 2015.
  5. Burns: a comprehensive assessment and treatment approach: a review. Wound Healing Southern Africa. Jan 2014.
  6. Pressure ulcers: surgical intervention. Wound Healing Southern Africa. Jan 2014.
  7. Suicide cases investigated at the state mortuary in Bloemfontein 2003-2007. Family Practice Journal. Jul 2009.

Dr PTD Nkosi

Qualifications
Qualification Field of Study University Year Completed
MBChb Medicine MEDUNSA 1992
DIP OBST(SA) Medicine CMSA 2007
DIP HIV Management HIV Management CMSA 2012
DIP Occ Health Occupational Health UKZN 2013
Work Experience
Period Position Employer
1994 - Current General Practitioner / Director (Treating HIV patients) Private Practice
2000 - 2013 Medical Doctor Ladysmith Provincial Hospital
2005 - 2013 Medical Doctor Government Clinic (Ladysmith DoH)
2014 – Current Sub-Investigator Qhakaza Mbokodo Research Clinic
Studies
Year Protocol Number Designation
2014 – 2016 IPM 027 Sub-Investigator
2014 – 2019 IPM 007 Sub-Investigator
2016 – 2019 IPM 032 Sub-Investigator
2014 – 2015 FACTS 001 Sub-Investigator
2016 – 2019 ECHO Sub-Investigator
2016 – Current HVTN 108 Sub-Investigator
2017 – Current HVTN 702 Sub-Investigator
2018 – Current HVTN 705 Sub-Investigator
2020 – Current HVTN 405 Sub-Investigator
2020 – Current VAC31518COV3001 Sub-Investigator
2021 – Current CoVPN 5001 Sub-Investigator
2021 – Current VAC31518COV3012 Sub-Investigator
2021 – Current CoVPN 3008 Sub-Investigator
2021 – Current MK8591-022 Sub-Investigator
2021 – Current VAC31518COV30XX Sub-Investigator
2022 – Current Sisonke 4 (SHERPA) / mRNA-1273-P508 Sub-Investigator
2022 – Current INSIGHT Cohort Sub-Investigator
2022 – Current GS-US-412-5624 Sub-Investigator
2024 – Current HVTN 605/A5421 Sub-Investigator
2024 – Current MK8527-007 Sub-Investigator
2024 – Current Gates MRI-TBV02-301 Sub-Investigator
2024 – Current Pfizer C3671032 Sub-Investigator
2024 – Current MK8591A-053 Sub-Investigator

Dr S Behariram

Qualifications
Qualifications Field of Study University Year completed
MBChB Medicine UKZN 1987
MFAM MED Medicine UKZN 1998
Certificate in Crisis Intervention Domestic Violence Advise desk for the abused
Certificate in Religious Studies Hinduism Ramakrishna Centre of South Africa (Faculty in Spirituality)
BLS Emergency Care American Heart Association 2013
Work Experience
Period Position Employer
Internship Ladysmith Provincial Hospital
Post Internship Medical Dept (Obstetrics & Gynaecology)
Ladysmith Provincial Hospital
1990 – Current General Practitioner Private Practice
1999 – 2013 Sessions Clinic SANDF Military Base – Ladysmith
2004 – 2013 Grade 2 Medical Officer Crisis Centre - Ladysmith Provincial Hospital
2007 – Current Trauma Doctor La Verna Private Hospital
2012 – 2019 Sub-Investigator Qhakaza Mbokodo Research Clinic
2020 - Current Sub-Investigator Qhakaza Mbokodo Research Clinic
Studies
Year Protocol Number Designation
2013 – 2016 IPM 027 Sub-Investigator
2014 – 2019 IPM 007 Sub-Investigator
2012 – 2015 FACTS 001 Sub-Investigator
2016 - 2019 ECHO Sub-Investigator
2016 – 2019 IPM 032 Sub-Investigator
2017 – 2019 HVTN 108 Sub-Investigator
2020 - 2024 HVTN 702 Sub-Investigator
2020 - 2024 HVTN 705 Sub-Investigator
2020 - 2024 HVTN 405 Sub-Investigator
2020 – Current VAC31518COV3001 Sub-Investigator
2021 – 2024 CoVPN 5001 Sub-Investigator
2021 - Current VAC31518COV3012 Sub-Investigator
2021 – Current CoVPN 3008 Sub-Investigator
2021 – Current MK8591-022 Sub-Investigator
2021 - Current VAC31518COV30XX Sub-Investigator
2022 – Current Sisonke 4 (SHERPA) / mRNA-1273-P508 Sub-Investigator
2022 – Current INSIGHT Cohort Sub-Investigator
2022 – Current GS-US-412-5624 Sub-Investigator
2024 – Current HVTN 605/A5421 Sub-Investigator
2024 – Current MK8527-007 Sub-Investigator
2024 – Current Gates MRI-TBV02-301 Sub-Investigator
2024 – Current Pfizer C3671032 Sub-Investigator